A container of Woods Areca Nut Toothpaste at the Museum of Human Disease
Woods Areca Nut toothpaste, sold in Europe during the late 19th century, was made from the pulverised charcoal of betel nuts, also known as areca nuts. While the toothpaste turned teeth black during use, it reduced the incidence of dental decay. I've posted an information sheet here about the history of areca nut toothpaste.
Chewing red betel nut fruit is custom in many Asian and Oceanic countries for it's mild stimulant effect. However, the practice is now widely discouraged, as the carcinogenic properties of the betel nut places regular chewers at risk of mouth and oesophageal cancer.
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